All of DirectedEvolution's Comments + Replies

For me, palatability is about texture at least as much as taste. What I've found, unfortunately, is that even the best imitation meats, like beyond burgers, certain vegan sausages, and chick'n, are in the uncanny valley of meatlike textures. I agree with you that chicken is rather bland on its own, and if an imitation chicken could nail the texture, I would probably be fine crossing over.  Red meat supplies much of its own flavor, and beyond burger and its similars have yet to really approach either the texture or flavor.

I think vegan sausage might be... (read more)

1
FlorianH
6mo
Surprised. Maybe worth giving it another try, looking longer for good imitations - given today's wealth of really good ones (besides admittedly a ton of bad, assuming you really need them to imitate the original so much): I've made friends taste veg* burgers and chicken nuggets and they were rather surprised when I told them post-hoc that these had not been meat. I once had to double-check with the counter at the restaurant as I could not believe what I had in my plate was really not chicken. Maybe that speaks against the fine taste of me and some, but I really find it's rather easily possible to find truly great textures too if one really cares. Then, I personally don't know any "uncanny valley" in that domain; make it a bit more or less fake feeling, it doesn't really matter much to me, so maybe you really experience that very differently. *I don't know/remember whether vegan or vegetarian.

I'm sure that it would be difficult to eliminate all unethical meat consumption, and I applaud you for trying before you went entirely veg*an. I don't have a very absolutist take on it. "Morally safe" is a relative term to me, and I don't feel like a moral disaster has occurred if I eat factory farmed meat once in a while. It's a bit like how I approached COVID safety: I will accept greater levels of harm/risk in order to enjoy a socially meaningful experience than I will in circumstances that are less meaningful. Similarly, I'll eat ethical meat at home a... (read more)

1
Drew Housman
8mo
Just in case it wasn't clear in my post, I am very interested in this approach as well! I applaud you for thinking along these lines. Every little bit helps. This Future Perfect article titled "the difference you make when you eat less meat" does a great job of showing how eating less meat can make a big difference in terms of animal welfare and climate concerns.  I think basically all of veganism is just degrees of this harm reduction approach. Someone like Brian Tomasik might look at my supposedly vegan lifestyle and weep, seeing that I crunch springtails underfoot when I walk in my lawn, I buy some produce that was grown with pesticides, and I buy non-vegan products for my wife and other family members.  If more people took your 80% approach there would be far fewer conscious animals tortured in tiny cages. Which would be a huge win. 

Based on your intro, I take it that you are one of the authors of the pain scale. It's been a while since I thought about this post, but I appreciate your info-dense comment, and given your apparent background I will take some time to read and think about it over the next week. It might be a bit before I can offer a substantive reply, but thank you for chiming in!

Overall I have been pleasantly surprised at how constructive this conversation has been, thanks to OP for creating space for it. Generally I find ethical discussion with EAs to be pleasant, but I had anticipated there might be an exception where veg*ism is concerned.

I would add one extra point, which is that while I do think that all of life's activities come into the scope of ethics, I think it's important to preserve space to make meaningful decisions without subjecting each one to conscious ethical deliberation. By analogy, sometimes we scrutinize all t... (read more)

Thanks for the information!

I'm curious, do you consider veganism more than "morally safe" if the meat-eater takes scrupulous care to source pasture raised and what we might call "artisanally slaughtered" meat and other animal products?

It kind of makes sense to me that veganism and being anti-abortion would go together - the points of view harmonize well. I personally have the opposite view, and think that both abortion and eating ethically raised meat are basically fine, even though many factory farming practices are apalling and there are probably some ca... (read more)

4
Ariel Simnegar
10mo
Thanks for the response! I think the care required to be a "morally safe" meat eater would have to be very scrupulous indeed. Effectively, one would have to be vegan when eating food bought by others, unless they are confident that the buyer shares their philosophy of scrupulously verifying humane raising and slaughter. * Almost all restaurants optimize for cost reduction when sourcing their animal products, so one would eat vegan at restaurants. This also means being vegan for Uber Eats, street food, food at the baseball game, etc. * Anytime one goes to a friend's house, they shouldn't eat the friend's meat, unless they know the friend shares their philosophy, or they had the friend specifically buy the meat for them. This means being vegan or extremely scrupulous for barbecues, hangouts, etc. I scrupulously kept kosher during my childhood and adolescence, which seems to require a similar level of effort. I almost never ate out, except at the single-digit restaurants in my town which were certified kosher. At baseball games, I had drinks but not food. I didn't eat any meals prepared at my non-religious or non-Jewish friends' houses, unless it was obviously raw (like a carrot) or in kosher packaging (like kosher snacks). Let me tell you, that was a lot of work! Even though veganism is much more restrictive, I actually find it far easier to keep, since it's relatively easily verifiable and communicable.

Yes, my partner keeps chickens in the backyard, so that's the only eggs I typically eat, and we are considering buying a meat freezer and ordering shares of pasture-raised livestock instead of buying at the supermarket. I tend to think that eating meat is more or less perfectly fine as long as the animal didn't suffer excessively during its life. I think that's less of a morally safe position than not eating meat at all. I'd personally like to see more consideration (not necessarily endorsement, just consideration) within the EA movement of pasture-raised/... (read more)

5
Jason
10mo
I found this to be a very helpful comment. In some of the recent discussions about veg*nism, I felt most people were assuming an implied binary choice between going vegan and ratifying the factory-farming system by consuming its products. We domesticated animals over 10,000 years ago, and have been eating them for thousands of years before factory farming was a thing. How to obtain animal products without factory farming is, from a historical perspective, a solved problem.[1] For people who have sufficient financial resources and some motivation, the biggest barrier may be differentiating between companies who want you to believe their products are consistent with animal welfare and those that actually are. To be sure, non-FF animal products are expensive, and one could achieve more impact by donating the marginal additional cost to ACE-recommended charities. However, some of us have deontologists and virtue ethicists in our moral parliament. And consuming factory-farmed products likely generates epistemic bias through cognitive dissonance (e.g., by making it harder to expand the moral circle). Moreover, the extra cost of purchasing non-FF animal products should probably be considered a personal cost of one's consumption choices, not a part of one's effective altruism. People spend their own money on stuff that isn't very effective in an EA sense (like pets), and that's fine. 1. ^ Of course, non-FF animal products are generally not financially competitive with FF ones. That is not a solved problem.

Good information and worth sharing.

I'm going to share some information about my meat-heavy diet, not because I'm trying to troll or distract from this post, but because I think there is value in trying to triangulate between the experiences of successful vegans and continued meat-eaters. The theme here is "refuting anti-vegan myths," and, on reflection, my resistance to becoming vegan comes from a different source, which I'll share in case anybody else has information that might be relevant.

I eat meat, and am currently dieting for the first time after ball... (read more)

9
Drew Housman
10mo
Thanks for the interesting comment and dialogue!  This part stood out to me, because I had the opposite reaction: I used to love eating meat. When I went vegan I realized I could get just as much satisfaction from any protein rich, umami-filled, sauce covered or well seasoned food. My pet theory is that what everyone mostly likes when they eat animals is the added sauces and seasonings, not the meat. Bland, unseasoned chicken breast is terrible.  But like I said in my post, I don't have a refined palate, so maybe to those with better taste buds meat really is that delightful. 

What I've rarely or never seen are anecdotes from "reluctant vegans" - people who, despite hating vegan food, not particularly feeling passionate about veganism, not having vegan friends, and missing on the easy sharing of meat-based meals with friends and family, nevertheless have made a principled choice to be vegan over the long-term purely on the grounds that it's a morally safe choice. If I did see such anecdotes, I think that understanding why and how they made the switch might be helpful in making the switch myself.

This largely applies to me.

  • Growing
... (read more)
5
RachelM
10mo
"I also don't share the intuitive impulse to not eat meat. I've owned pets, I've watched the documentaries about factory farming, I've worked with animals on farms, I've read the essays about animal cognition, and none of that has sparked a particular intellectual or emotional impulse to not eat meat." Has any of that changed the kind of meat you eat, in terms of how the animals lived and died? I do get the argument-from-deliciousness (the sheer enjoyment of really good cheese is why I'm not fully vegan despite having been happily vegetarian for >30 years), but I'd find it really hard to eat, say, something containing eggs from caged hens. The visceral horror would outweigh any good sensory feelings, for me. Do you encounter any of that?

Thanks for your thoughts!

I agree that more refined metrics would allow a better comparison between deaths from malaria in Africa and deaths from kidney disease in America.

A typical story for the latter is “a Black man close to retirement suddenly develops the symptoms of end-stage kidney disease and is put on dialysis. If he receives a kidney, he lives until his late 70s-early 80s in health comparable to if he hadn’t experienced kidney failure. If not, he declines and dies a few years later.” Kidney transplants typically give about 15 years of extra life b... (read more)

This is excellent, thank you very much for writing this all out. I really appreciate it. I'll reply with questions if they come up.

We can imagine many ways of specifying a pledge that is substantial and targeted at effective charities.

One example might be a pledge for which the fraction of income to be donated is itself a function of income (perhaps a 0% donation is called for if you make < $10,000/year, and a max of 50% is called for if you make > $100 million/year, with the % of income scaling in between these bounds). But that of course is much more than "10% of income."

How do you think on a meta-level about the tension between the need for simplicity and the risk of oversimplification in GWWC's messaging?

Part of GWWC's mission is to create a culture of giving, but as you note in comments, a huge proportion of your donations come from the wealthy. How helpful do you think it would be if we thought about creating cultures of giving, with a focus on the intersectional - considering the ways that income, race and ethnicity, religion, nationality, and so on intersect with habits of charitable giving?

How much does GWWC prioritize getting people to commit to the GWWC pledge specifically, as opposed to spreading earnest commitment to the twin ideas of:


1. Higher than normal levels of charitable giving?

2. Selecting recipients of charitable giving based on (secular) impact?

For example, if the result of GWWC's advocacy was convincing a profoundly religious person to donate more to their church's missionary activities, believing that this is the most effective way to save souls, would GWWC consider that a success?

What role(s) do you see GWWC playing in onboarding new people into EA? Are people finding GWWC's website as their first point of contact with EA, perhaps discovered via Google? Are they reading books like What We Owe The Future and finding it that way? Are they discovering GWWC after onboarding into EA some other way?

It seems to me like there are two somewhat common critical interpretations of the 10% GWWC pledge.

  1. The idea that the standard is 10%, so anything less than that is a failure or not good enough.
  2. The idea that although we only ask for a pledge of 10% of one's income, we are asking that 100% of pledger's charitable donations go specifically to effective charities - no room for donations to the arts, one's alma mater, etc.

Do you think that the 10% GWWC pledge is, in fact, often interpreted that way? If so, do you think there is any value in modifying the pledge ... (read more)

I am not clear on if that number is meant to be interpreted in terms of years or just as a unitless "moral weight" for comparison purposes. I am hesitant to compare it with QALYs or other metrics without knowing the units.

6
Lorenzo Buonanno
10mo
The spreadsheet in the second link says YLL (years of life lost) which I think can be considered equivalent to QALYs in this case. It's also consistent with the comment on the 0.40 on the conventional value of increasing income in the first spreadsheet

I don’t think there’s a substantive difference. It’s just counterfactual reasoning. If I give you penicillin that saves your life so you live to age 70 instead of dying at 25, did I just save or create 45 years of extra life for you? I think that is just a matter of word choice.

Interesting. That is not apparently taken into account in the $4500/life figure they publish which is based exclusively on deaths averted.

Hm interesting. It's plausible this is a way to avoid utility monsterization?

Like hypothetically, let's say an average high-income life is twice as enjoyable than a low-income life. If that were the case, then using cost-per-QALY might give an advantage to saving high-income lives - they were all set to have a fun life as a rich person until they happened to die from some disease. Whereas the low-income lives were going to have a miserable time anyway, so it "doesn't matter as much if they die." I am not endorsing this interpretation - just articulating what using QALYs might imply if we were to use them for comparison purposes.

3
Lorenzo Buonanno
10mo
You can read their GiveWell's public document on DALYs here A thing that might be worth noting is that according to GiveWell ~40% of AMF's value comes from increasing the long-term income of children, not from health outcomes

I liked Lucretia's initial response quite a bit. For a small bit of context about my personal identity and background, I'm a hetero cis man who has witnessed severe problems with sexual abuse in the rat/EA and also in other subcultures over the last 10 years, and has had many conversations with women on these issues.

The following are just my thoughts. Their length, the number of conjunctions, and the fact that I'm a hetero cis man makes me a little bit anxious about posting them, even though I think they are a carefully thought-out and constructive contrib... (read more)

Update:

I'm going to take a stab at a framework. This is the first time I've written this down, so consider this possibly prone to errors and in draft status.

Instead of lumping all types of sexual harassment/abuse together, we could view sexual abuse/harassment as structurally similar to first, second, and third degree homicide, with varying degrees of intent.

Type 1 sexual abuse/harassment may involve calculation and intent. Epstein, Weinstein, and Ratrick's actions above in studying red pill scripts would fall under Type I. You can see that this behavior w... (read more)

3
Lucretia
10mo
This is a great answer, thank you. The context-dependence of some sexual abuse is also why it can take some survivors awhile to process and articulate their experiences. The process can feel like picking jagged glass out of an organ. I don't have great answers yet, but appreciate the frameworks you're developing.

In fact, ignoring concerns about message complexity and not trying to be too fancy, I might suggest we eliminate any hard percentage standard in favor of a recommended % donation that scales with income. So somebody earning < $10,000-$20,000/year might be advised not to donate. Someone earning $80,000 might be asked to donate 10%. Someone earning $10,000,000/year might be asked to donate 90%. These are just rough numbers. But I think this might be better treated in book form or in tailored appeals to individual people. In the EA community I think it wou... (read more)

2
Jason
10mo
That would be more accurate, but doing it well would start to feel like a tax return. But going on income alone without considering cost of living, debt obligations, family size, etc. would produce inaccurate results.  Maybe it could be a range -- e.g., We recommend the average person earning $80K a year donate 11%; for most people at this income we would recommend donating somewhere between 8-14% depending on personal circumstances. (I changed 10 percent from your example to 11 percent as a starting point, because I think the median person would assign themselves a slightly-less-than-median point in the range.) 

Hi Jason, thank you for your response.

To the extent "you should only donate to effective charities" is being conveyed in practice, it's not clear to me why deploying a 2/8 message is the most effective way to correct that mismessaging.

It's certainly not the most effective way in all circumstances. I think that, on a substantial the margin, a 2/8 message would be more effective in many circumstances. I think a sophistated EA take would be that the real goal is to find a substantial yet isustainable level of giving to effective causes, one that is tailored t... (read more)

2
Jason
10mo
I think you've hit on one of the challenging bits here -- what the 10% represents is not particularly well defined, certainly not to someone just encountering EA ideas. We can approximate the intent with metaphors or phrases like "community standard," "some sort of moral claim," "green tether," etc. But if we're assuming a target audience who hasn't "encountered this complex bundle of ideas and aren't going to give us a huge amount of time before writing us off," then we can't assume any kind of nuanced understanding of what the pledge represents.  If I understand the perceived problem you're trying to fix correctly, the theory is that at least a meaningful fraction of the target audience is going to misinterpret the community standard as somehow precluding or discouraging less-effective donations out of the 90% -- even though this is a pretty unreasonable interpretation to start with, [1] and can be disclaimed pretty early in a presentation. To me, a more plausible inference would be to read the standard as embodying a claim that following the standard is morally obligatory -- or at least significantly morally superior -- to not following it, at least for a median-income adult in a developed country with no special circumstances.[2] And if the listener comes in with that inference, the 2/8 standard seems much harder to justify as a philosophical matter than the 10% standard. And that seems like a significant downside to me, given that EA has had more success with philosophically-minded people. In the end, some of what we're discussing touches on empirical questions that Giving What We Can might find worth evaluating. When presented with brief information about the GWWC pledge, what beliefs about the community standard do people endorse? How do various ways of explaining the community standard effect the listener's understanding? That's not about trying to manipulate people; it is seeing if the way things are being communicated faithfully conveys the community's

For example, can I do better than just deferring to the “largest and smartest” expert group on “Might AI lead to extinction?” (which seems to be EA). Can I instead look at the arguments and epistemics of EAs versus, say, opposing academics and reach a better conclusion? (Better in the sense of “more likely to be correct”.) If so, how much and how should I do that in the details?

 

Deference is a major topic in EA. I am currently working on a research project simulating various models of deference.

So far, my findings indicate that deference is ... (read more)

3
FinalFormal
11mo
The idea of deferring to common wisdom while continuing to formulate your own model reminds me EY's post on Lawful Uncertainty. The focus was an experiment from the 60s where subjects guessed card colors from a deck of 70% blue cards. People keep on trying to guess red based on their own predictions even though the optimal strategy was to always pick blue. EY's insight which this reminded me of was:

Hi mhendric,

Thanks for your feedback! Researching and writing up my posts takes enough time that adding in individual zoom calls on top would be tough - I work full time. Maybe at some point?

I see two strains of EA criticism. The one you point out comes from EA’s ideological opponents. That doesn’t mean they are bad, wrong, or that their lives revolve around some sort of other political activism. It means that they have decided on a different organizing ideology for their worldview that generates conclusions incompatible with EA’s way of looking at a varie... (read more)

Update: based on analytics and timing, I now believe that there are one or two specific individuals (whose identities I don’t know) who are just strong-downvoting my posts without reading them.

While they may be doing this because they disagree with what they can glean of my conclusions from the intro, I do not consider this to be different from suppression of thought. I am not certain this is happening but it is the best explanation for the data I have at this time.

I continue to find the speed at which these posts accrue initial at least one initial early strong-downvote surprising and frustrating. Once again, I invite downvoters to articulate their disagreement in a comment. Based on analytics, I know it is one of the first 6 readers, and that they spent less than 5 minutes on this 11 minute article. I precommit to responding with a "thanks for your feedback" or something more positive and thoughtful than that.

I hope you will join me for further discussion and debate in my next post, where I dig in deeper to some of the objections you raised here!

As one additional note, first, thank you for linking to the survey about people's familiarity with EA. Although I think it is probably useful evidence, and am extremely supportive of attempts to gather such evidence in general, one of my immediate concerns is that the data was gathered in April 2022.

This means the results predate both Will MacAskill's high-profile publicity tour for What We Owe The Future as well as the downfall of FTX. My guess is that the number of people who have heard of Effective Altruism has increased substantially since then. The Ne... (read more)

2
David_Moss
11mo
I think the numbers initially claiming to have heard of EA (19.1%) are strongly inflated by false positives (including lizardmen), but the numbers after the 'stringent' checks (including giving a qualitative explanation of what EA is) were applied (1.9-3.1%) are much less so (though, as we argue, still somewhat inflated). Note that the org results didn't have the same checks applied, so those definitely shouldn't be taken at face value and should be expected to be inflated by lizardmen etc. We'll be publishing results about this soon, but as we noted here, we don't think there's been such a substantial increase in awareness of EA due to FTX, including among elite groups.

Yes, I have tentative plans to conduct some interviews and MTurk surveys as a cheap and easy way to gather more empirical information. I don't think these will resolve the question, but hopefully they will continue to elevate the discussion with critique that is less focused on convenience sampling and ad hoc interpretation by a potentially motivated debater (which is how I would criticize the quality of the evidence I present here).

That makes sense, and thank you for providing that context for your vote. Part of the challenge here is that our differences seem to be the result of more than one belief, which makes it challenging to parse the meaning of upvotes and agreevotes.

Thank you Isaac. Based on this post's more positive reception, I'm more inclined to update in favor of your view.

Hi mhendric. First, thank you for your continued engagement and criticism - it sharpens my own thinking and encourages me to continue. I will respond in greater depth to some of the critiques you've made here in my next post.

Briefly:

  • My wording obviously has been muddy. My proposal is not a mandatory 2%-to-fuzzies-causes pledge, but a 10% pledge of which 80% is allocated to effective causes and 20% is explicitly to whatever cause the donor is passionate about. This discretionary 20%-of-the-10% (i.e. 2% of annual income) could also go to effective causes, bu
... (read more)

Thank you for your response.

I completely agree that earning to give and the GWWC pledge are conceptually distinct. Ideally, anyone dealing with these ideas would treat them as such.

Where I disagree with you is that my post is conceptually 'conflating' these two ideas. Instead, my post is identifying that a bundle of associated ideas, including the GWWC pledge and earning to give, are prominent parts of EA's reputation.

Here is an analogy to the point I am making:

  • When people think of engineering, they think of math, chemicals and robots.
  • When people think of
... (read more)

To readers of this post, I would like to note that a small number of people on the forum appear to be strong-downvoting my posts on this subject shortly after they are published. I don't know specifically why, but it is frustrating.

For those of you who agree or disagree with my post, I hope you will choose to engage and comment on it to help foster a productive discussion. If you are a person who has chosen to strong-downvote any of the posts in this series, I especially invite you to articulate why - I precommit that my response will be somewhere between "thank you for your feedback" and something more positive and engaged than that.

My guess it's that it's an unfortunate consequence of disagree voting not being an option on top-level posts, so people are expressing their disagreement with your views by simply downvoting. (I do disagree with your views, but I think it's a reasonable discussion to have!)

See my new post for a partial response to this portion of your argument:

Firstly, I don't see any benefit from the proposal.  I don't think the 10% norm forms a major part of EA's public perception, so I don't believe tweaking it would make any difference.  If anything 2%/8% makes it more weird (not least because it no longer matches the tithing norm).  You haven't made any compelling argument for the reputational advantage to be gained either here or in your previous post, yet alone that this is the most effective way of gaining reputation.

See my new post for a partial response to this portion of your argument:

I'm not really seeing a dire need for this proposal. 10% effective donations has brand recognition and is a nice round number, as you point out. It is used by other groups, such as religious groups, making it easy to re-funnel donations to e.g. religious communities to effective charities. This leaves 90% of your income at your disposal, part of which you may spend on fuzzy causes. It does not seem required to me to change the 10% to allow for fuzzy donations, nor do I think there's a

... (read more)
1
mhendric
11mo
I appreciate the notification and will take a look!

Although you are right that modesty (or deference) often outperforms one's own personal judgment, this isn't always the case. Results below are based on Monte Carlo simulations I haven't published yet.

Take the case of a crowd estimating a cow's weight. The members of the crowd announce their guesses sequentially. They adopt a uniform rule of D% deference, so that each person's guess is a weighted average of a sample from a Normal distribution centered on the cow's true weight, and of the current crowd average guess:

Guess_i = D*(Crowd average) + (1-D)*(Dire... (read more)

Thanks for your thoughtful comment. Based on your comment and others, I am going to focus my next post in this series on how I think about movement reputation in general, including some specific replies to your points here. Just flagging that lack of a substantive reply here is because I'm going to write a full-scale post on the subject, hopefully over the next few days.

That makes sense. I don't think there are any official prerequisites to being an EA, but there are community norms. I think the GWWC pledge (or a direct-work equivalent) is a common-enough practical or aspirational norm that I'm comfortable with eliding EA and GWWC-adjacent-EA for the purposes of this post, but I acknowledge you'd prefer to split these apart for a sensible reason.

I'd guess donating for warm fuzzies is generally an ineffective way to gain influence/status.

As a simple and costless way to start operationalizing this disagreement, I claim that if I ask my mom (not an EA, pretty opposed to the vibe) if she'd like EA better with a 2%/8% standard, she'd prefer it and say that she'd think warmly of a movement that encouraged this style of donating. I'm only sort of being facetious here - I think having accurate models about how to build reputation for the movement are important and that EAs need a way to gather evidence and update.

My post is related to the Giving What We Can pledge and the broad idea of focusing on "utilons, not fuzzies." From the wording of your comment I'm unclear on whether you're unfamiliar with these ideas or whether you are just taking this as an opportunity to say that you disagree with them. If you don't think that standards like the GWWC pledge are good for EA, then what do you think about the 2%/8% norm I propose here as a better alternative, even if far suboptimal to no pledge at all?

6
Daniel_Eth
11mo
I don't think taking the GWWC pledge should be a prerequisite to consider yourself an EA (which, it's not a prerequisite now). If your post had said "GWWC members should..." or "EAs who donate 10% should..." instead of "EAs should..." then I wouldn't have disagreed with the wording.

Roughly, I think the community isn't able (isn't strong enough?) to both think much about how it's perceived and think well or in-a-high-integrity-manner about how to do good, and I'd favor thinking well and in a high-integrity manner.

Just want to flag that I completely disagree with this, and that moreover I find it bewildering that in EA and rationalism this seemingly passes almost as a truism.

I think we can absolutely think both about perceptions and charitable effectiveness - their tradeoffs, how to get the most of one without sacrificing too much of t... (read more)

I would not be surprised if this small cohort of volunteers accelerated the pace of getting to this result by a year or more. I'm not going to take a chance on plugging in numbers, but that's a lot of lives saved per volunteer. While most of the badass points/moral credit goes to the people who received the jab, we should also feel proud of the people who were lined up behind them ready to endure the same.

4
Brad West
1y
Assuming the genuine willingness of volunteers who ended up not being selected, I do not see a differing level of moral praiseworthiness based on the fortune/misfortune of not having the opportunity to be a part of the study.

I have a second question. You compared before/after intervention malaria rates for the treated vs. control districts, and found that the multiplier was 52.5% lower in the treated areas. Do we have information on how this compares to historical data? Also, were the districts randomly selected for the treatment vs. control group, or was it chosen on a convenience basis?

I am thinking about the possibility that the treated and control districts may have significantly different base rates of malarial increase at the seasonal time points chosen for the before an... (read more)

9
Arnon Houri Yafin
1y
Thanks again. This, too, is a good point.  First of all, a small clarification - we are seeking $6M for various purposes; the cost of the RCT should be about $1.5M. To the main point: historical data from the Ministry of Health on Anopheles mosquitoes supports the same conclusions but was not included in the publication (history of malaria data per district has not been shared with us by the government). As highlighted in the paper, the intervention was a pilot and NOT a clustered randomized control trial (cRCT), though it was the Ministry of Health (and not us) who selected the intervention and control areas.  In other words, we do need a cRCT to fully validate our method, but the existing evidence is definitely strong enough to justify spending $1.5M on rolling out such an cRCT.  Hope this answers your questions. Let me know if something is still unclear.  Thanks!       

This looks like excellent work, a very logical intervention and where you’ve put a lot of effort into putting together the data to attract serious funding for a scale-up.

One thing I would like to know: in urban areas, I presume access to medical care is higher, and so I am wondering whether the death rate, as well as incidence, may be lower. I see that you achieved a 52% reduction in cases, and I am wondering if you have data, or will be gathering data, on the effect on deaths due to malaria?

7
Arnon Houri Yafin
1y
That's a valid point. Morbidity and mortality rates are indeed lower in cities, and I attempted to reflect this in my calculation. However, if someone has more accurate data, I would be happy to update my calculations. Designing an experiment around death is extremely challenging because it requires 200 times more area to achieve the same statistical power.

I have also encountered deletionism. When I was improving the aptamer article for a good article nomination, the reviewer recommended splitting a section on peptide aptamers into a separate article. After some thinking, I did so. Then some random editor who I’d never interacted with before deleted the whole peptide aptamer article and accused me of plagiarism/copying it from someplace else on the internet, and never responded to my messages trying to figure out what he was doing or why.

It’s odd to me because the Foreign Dredge Act is a political issue, whi... (read more)

That hasn’t been entirely my experience. In fact, when I made the page for the Foreign Dredge Act of 1906, I was pleasantly surprised at how quickly others jumped in to improve on my basic efforts - it was clearly a case of just needing the page to exist at all before it started getting the attention it deserved.

By contrast, I’ve found that trying to do things like good article nominations, where you’re trying to satisfy the demands of self-selected nonexpert referees, can be frustrating. The same is true for trying to improve pages already getting a lot o... (read more)

4
niplav
1y
Epistemic status: ~150 Wikipedia edits, of which 0 are genuine article creations (apart from redirects). I've mostly done slight improvements on non-controversial articles. Dunno about being a novice, but looking at your contributions on WP you've done more than me :-) I was thinking mostly of the fact that you need to be autoconfirmed, i.e. more than 4 days old and ≥10 edits. I also have the intuition that creating an article is more likely to be wasted effort than an improvement to an existing article, because of widespread deletionism. An example for the deletionism is the Harberger tax article, which was nearly removed, much to my dismay. Perhaps this is more true for the kind of article I'm interested in, which is relatively obscure concepts from science (with less heated debate), and less about current events (where edits might be more difficult due to controversy & edit wars).
Load more