Thanks for the thoughtful write-up! A few things came to mind while reading:
Part of the post felt like a false equivalency - to my knowledge $100M spent on animal welfare would actually net virtually no funds to conservation, as opposed to other approaches. Indeed as CB pointed out, many of the ideas people are pursuing are anti-conservation (I admit I am biased against funding wild animal suffering programs) - they actually openly advocate for further manipulating ecosystems.
One particular section also caught my eye: "Zoonotic diseases, such as Ebol
I don't know if this is what you are envisioning, but check out Blue Ridge Labs - they do a fellowship where they get techies to apply to an 'incubation period' focused on solving a social issue and teams form during the initial discovery phase. Many startups get major funding and are profitable.
Could be a good format to follow.
Congrats on the baby - I hope all are well! This is very cool, and glad to hear that others have thought about this as well. A virtual (or physical!) card game is definitely a modality that could work for this as well. I've separately thought that a card game would be great for an adversarial board game would be something around nuclear armament with different players playing as different countries, etc etc.