Awesome! Will do, thank you!!!

Thanks Vasco!!!

Thanks for the comment Marysabel; so much still needs to happen, and we know there are so many committed people (like yourself) willing to take on the challenge!

Thanks Patrick, very grateful for all the support!!!

Thanks Vasco, hugely appreciated! 

Hi Vasco,

Thanks for the question, happy to answer.

The CEAs were built with different levels of involvement from the fellows, our team, and LLM support. Claude being the main supporting tool.

The template and overall structure of the CEAs were developed outside of Claude, based on our methodology (and heavily comparing different templates from different organizations). 

As for the content of the models:

• Costs: fellows first analyzed the cost structure of the interventions they were drawing evidence from (i.e., understanding the key cost drivers). Based on that structure, they built localized budgets using country-specific prices and costs. All organizational budgets were developed by the fellows within our template for direct implementation, with those benchmarks and certain assumptions, we calculated the intervention cost at scale, so no Claude involvement here.
• Key assumptions: (e.g., reach, limiting factors) were fully defined by the teams, based on their contextual knowledge, and we then used scale factors, to project reach at scale, so no Claude involvement here.
• Evidence: (RCTs, meta-analyses, etc.) was reviewed as part of the research process (we used other LLMs for this as well, mainly Elicit and Perplexity); Claude mainly helped structure and organize the information within the template.
• Calculations: were done with Claude, but step by step, so we reviewed every output generated (making this the most time-consuming part of the process). I can confidently say we reviewed every cell, adjusting assumptions, asking questions, and catching errors. Of course, this is also the part where errors are most likely to occur, and these are only the first versions of the models, so I am also confident that there are still mistakes we did not catch.

Once the models were completed, we held review sessions with each team to revisit key assumptions and refine the models. For example, asking whether certain implied assumptions made sense for the real world, and because the fellows themselves know their context and intervention details, many things were changed. However, the models are far from being final, but the template structure was created for them to be used as a planning tool (not only a fundraising tool), so teams will definitely adjust them with time and with their internal evidence, once available.

In full honesty, building the models was the part of the incubation process that scared me the most, so I’m very glad Claude appeared at the right time, and it also made me more confident in that using templates like this is a way to make CEAs more accessible: once organizations have clear cost structures (and many orgs have detailed budgets), assumptions, and external evidence, building a first model becomes much more feasible. It’s not perfect, but it’s a strong starting point.

Very happy to share the template or walk through it together, we’re very keen to improve it and learn further with feedback.

Thanks Brennan, always open to suggestions and feedback!

Hi Gabrielle,

Thank you for your thoughtful reflection.

Regarding the research question: while fellows are making the decisions, they are doing so within a fairly structured methodology (we provide the tools, templates, and step-by-step process). For example, problem selection is guided by specific thresholds (e.g. Only selecting problems that are affecting >600k people or ~6M animals in the first country of implementation), alongside other criteria like depth, breadth, and trajectory of the problem in the region.

Similarly, intervention selection is constrained by requirements such as being evidence-based (e.g. supported by RCTs, meta-analyses, or strong evidence equivalents for animal welfare), proven to be cost-effective in other contexts, and feasible to adapt locally. We also have a (small) research support team helping throughout the process. And of course, we have used the help of certain LLMs (like Elicit and Perplexity).

Additionally, fellows go through theoretical training (e.g. M&E principles) to guide their reasoning, and we have the support from IPA Colombia, who provided lectures and office hours to review parts of the work.

We don’t think this replaces the depth of a trained researcher, but in a resource-constrained setting, it allows for reasonably rigorous, structured decision-making. It also has the advantage of making the reasoning process explicit so if something doesn’t work (as it sometimes happens in the real world, while implementing), fellows can revisit and iterate more effectively.

Always happy to receive feedback on how to improve things!

Hi Tony, thanks for the thoughtful questions!

Regarding Ambitious Impact/CEIP, we’ve definitely drawn inspiration from their model and have received direct mentoring from them throughout our implementation. They have been very generous with their knowledge and support! Some key differences:

1. Founders act as researchers, guided by our methodology: they choose the problem (based on the ITN framework) and the intervention (evidence-based and cost-effective), and they decide what to focus on.
2. They build in their own countries.
3. They implement an early prototype during the incubation.
4. It’s a part-time program with a longer duration (12 months total) in their native language.
5. We don’t have a seed funding circle (yet), but we aim to demonstrate the types of interventions being incubated and build toward that over time.

Thanks for wanting to support! We are hosting a Meet the Founder session on April 9th to facilitate this; connections, mentorship, and feedback are exactly what we’re looking for. If you’d like to join, please fill out this short form (≈3 minutes), and we’ll share the meeting link and details: https://forms.gle/sb5bYBUihReiexJv8

It would be great to have you there!

As for the Laboratory of Social Entrepreneurship, we are a relatively new organization (~1 year), and this is our first cohort, but it builds on prior experience in the sector (M&E, program design, and implementation) and in the region.

Happy to share more if helpful, and thanks again for engaging!

Hi John,

Thanks for the comment and for flagging the issues.

1. We have solved the formatting.
2. & 3. Here is GRANA - Website for ease of exploring the organization.

Happy to talk if you would like more information!