84Joined Dec 2015


My worry is that you're probably trying to identify then add/turn-on too much (i.e. all of the genes that code for egg laying).

I'm sure its probably not straightforward to change shell colour, which would be the best method of identification of chick sex (maybe shell development is determined by the hen rather than the embryo?), but there's probably still a couple of additions you could make to the Z and W chromosomes to ultimately achieve the same outcome. And a couple of additions would likely be at least an order of magnitude easier than identifying then adding/turning-on a bunch of genes.

At least one idea that comes to mind is using insights from gene drive theory to disrupt male embryo development enough to be identifiable using a light shined through an egg. For instance, you could insert a gene into both Z chromosomes coding for a CRISPR complex that disrupts some key embryo development process. Additionally, you insert a gene into the W chromosome that codes for a CRISPR complex that modifies/disrupts the CRISPR complex on the Z chromosomes.

Maybe there's a really obvious reason why that wouldn't work or wouldn't be that simple, but I suppose my point is that maybe you should aim to find and pursue a more simple solution unless you're sure that no obvious and simple strategies would work.

Either way, I really hope you and your efforts succeed.

This is really great to see and just wanted to quickly say that the website looks fantastic. Great design.

Comprehensive archive of career routes of people currently at the top of the biosecurity industry (mainly for useful stats gathering eg how many degrees on average does each person have, what age did they get to the position they currently hold). 

Is anybody doing this project?

I work as a senior policy analyst in the New Zealand government, specifically in the area of genetic modification policy.  I can talk about how I got the job, and why I think I excel at it, despite not having a background in science, as well as what the work is like day-to-day.

Hi freedomandutility, I'd really like to hear more about this if you'd be happy to expand on it a bit and perhaps give examples etc. 

I tend to lose sight/forget the greater 'why' for why I'm pursuing certain things.

If 'Coordination for EA researchers' is considered by enough people to be a worthwhile project to undertake, I'd be interested in working on that (in a project design capacity).

And on a related note, I think combining this project with others like the 'EA expertise board' or 'Build a platform to match projects with people who can do them' would enable the platform to reach a critical mass of active users, making it really worthwhile for the community.

If the EA forum weren't (as far as I can tell) just filled with EAs, I'd agree.

I don't think we should necessarily be worried that, say, some journalist is reading this forum (which is what I take your comment to mean), so much that we should be worried that posts like this could potentially turn off people that are currently EAs or are considering becoming more involved in EA. Speaking personally, the suggestions floated in this post seemed a little dishonest to me.

Yeah, I agree with this.

Also, as a side note, I'd like to donate to MIRI in future but I'm currently based in Australia.

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