If I had to choose, I would donate to Malaria Consortium. Based on the information I have reviewed, they focus on interventions for young children, providing anti-malaria drugs and immunization to infants, which has the potential to prevent a significant number of deaths. By targeting children at an early age when their immunity is still developing, the impact can be substantial. Additionally, if there is a recommendation for early malaria immunization, the effect could be even greater.
With only $1,000 to donate, I would choose to support Helen Keller International. Their distribution of vitamins costs only $1 per dose, which means that with the available funding, I can reach a larger number of people and have a greater overall impact.
There are other decisions in life where it would be beneficial to generate quantitative estimates and compare outcomes. For example, when considering legal and medical interventions, it would be valuable to assess the potential benefits and drawbacks of each option to make an informed decision without neglecting any important factors.