ChristianKleineidam

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No More Pandemics: a lobbying group?

Whether or not the Wuhan Institute of Virology really was the cause of the  COVID-19 outbreak, it's a possible scenario that a lab that's focused on researching potential future pandemics has a security breach and accdiently starts a pandemic. 

When doing outreach it's worth to keep those risks in mind and hopefully focus on interventions that don't increase accidental risk. 

There are technologies such as CISPER that both make it easier to delibrately start pandemics and that also give us tools for fighting future pandemics. 

Asking experts that did research into what policy might be effective is likely import to get good results. 

No More Pandemics: a lobbying group?

Pushing policies that are popular is presumably much more tractable than pushing those that are not

If you push a huge bill for increased biosafety it's okay when there are policies included that don't poll well but for which you can convince legislators with good arguments. Especially when there's no lobby against the policy and it's unlikely that the issue will become the subject of public debate. 

Could we solve this email mess if we all moved to paid emails?

How would this be an "internal practice"? The only way this would work would be to have people publically post their earn addresses.

I think you underrate the cost of weirdness.

Let's say there's a journalist who wants to write a story where he might ask a high-status EA to comment because it falls into their domain expertise.

Then the journalist searches for ways to contact the EA and finds that the EA prefers to get cold approaches via this system. The journalist might think: "This is bad, I don't have a budget for this, paying sources is what evil people do". Even when the journalist then finds that there's a free way to contact the EA, they have their first contact with negative emotional attachment.

While the kind of his status EA that might be contacted this way might get more emails then they prefer, it's important for them to be easily contacted by outsiders because that allows for valuable interactions to happen.

Terrorism, Tylenol, and dangerous information

It's general easy for an IT organization to fix a bug once the bug is disclosed. It's not easy to close are vulnerabilities of physical security that might be discovered.

Closing what was revealed on https://www.schneier.com/blog/archives/2006/06/movieplot_threa_1.html would be very expensive in contrast to the work required to come up with the ideas.

On funding medical research

After different forms of resting https://curetogether.com/chronic-fatigue-syndrome/ig/treatment-effectiveness-vs-popularity Low-Dose Naltrexone seems to be the treatment that was reported as most beneficial on CureTogether for CFS. Fortunately there’s an ongoing clinical trial to test this treatment.

I think the fact that there are some pearls in alternative medicine but there no efficient way to find them is a more fundamental problem that is it’s own cause worth looking at. Our at LessWrong I wrote proposed Prediction-based Medicine. It would be possible to create a startup that puts Prediction-based Medicine to work and afterwards it would be possible for patients to go to alternative medicine providers who can reliably predict the treatment success they have for the patients.

The startup would need a good team and some funding but Musk-level funding wouldn’t be required to put the idea effectively to work.

On funding medical research

Your article doesn’t mention Systemic Exertion Intolerance Disease (SEID). It’s the new name the Institute of Medicine (IOM) gave the disease. Given that we are on the internet it’s helpful to work all relevant keywords into an article like this even if you don’t like the new name.

On funding medical research

Mind-Body dualism isn’t a productive framework. For many diseases you have a mix of “physical” and “psychological” effects.

Open Thread #38

I don't think the recent rise of polarization in the US over the last decade is driven by a rise in racism or sexism. Activism to reduce either of them might be valuable, but I don't think it solves the issue of polarization.

High Time For Drug Policy Reform. Part 4/4: Estimating Cost-Effectiveness vs Other Causes; What EA Should Do Next

I don't think the average nootropics user would appear to have a goal of getting a legal high in a television broadcast.

It's more interesting for a journalist to tell a story about a computer programmer who takes LSD to help him with a difficult programming problem on which he worked for months without a satisfying answer than to tell a story about the computer programmer wanting to get high with LSD.

The story about how nerds in Silicon Valley do everything to enchance their performance is more interesting than the story about a random person taking drugs.

More generally EA is also full of weird causes as Scott Alexander describes very well in his blog post about EA Global.

High Time For Drug Policy Reform. Part 4/4: Estimating Cost-Effectiveness vs Other Causes; What EA Should Do Next

http://www.maps.org/gmp :

Donate to Make MDMA a Legal Medicine

Research is showing that MDMA combined with psychotherapy can be an effective option for people who haven't been helped by other treatments for posttraumatic stress disorder (PTSD). PTSD can be caused by trauma from war, sexual assault, violence, accidents, natural disasters, and other stressful events.

You can help make MDMA a legal medicine and heal people suffering from trauma by making a tax-deductible gift to fund Phase 3 clinical trials of MDMA-assisted psychotherapy for PTSD.

[...]

We estimate that it will take $870,000 to complete our Phase 2 studies, and roughly $25 million to complete Phase 3 and establish MDMA-assisted psychotherapy as a legally available treatment.

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