Thanks, Max! One follow-up — you write:

If I were the czar of biosecurity resources, then I would probably only re-distribute them marginally differently and focus slightly more on broad defenses

I'm a bit surprised that this is true, given what seems to me from afar to be inordinately more spending and research on vaccines/MCMs relative to this entire bucket of passive interventions combined.

When you say "czar of biosecurity resources," are you thinking of the resources of national governments, those of this community, etc.? Or was there some other specific reference group you were thinking of? I'd also be curious if you could be a bit more quantitative about how much you'd prefer to shift to passive/broad mitigations on the margins, or even if you have takes on the relative distribution between items in that bucket (though also get that putting numbers on this is tricky).