Holden Karnofsky is the co-CEO of Open Philanthropy and co-founder of GiveWell. He is also the author of the always interesting Cold Takes blog.

This was a very interesting & wide-ranging discussion about Holden's thesis that transformative AI makes this the most important century. We also discuss whether he regrets OpenPhil’s 30 million dollar grant to OpenAI in 2016.

Highly recommend!

Watch on YouTube. Listen on Apple Podcasts, Spotify, or any other podcast platform. Read the full transcript here.

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Thanks for sharing! How much is this aimed at highly involved EAs vs people with no EA context? (ie, should I expect there to be a bunch of time explaining things I'm already familiar with/Holden has discussed on other podcasts).

I've been really enjoying some of your other episodes, thanks for making them!

[anonymous]1y11
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I think if anything people might be frustrated with how little context I was giving the uninitiated viewer haha. You can skim the transcript first to see how much new material there is: https://www.dwarkeshpatel.com/p/holden-karnofsky

Maybe skip the first 5-10 mins if you wish. Especially from 20 mins in, it gets pretty interesting!