All of PabloAMC 🔸's Comments + Replies

What would be the motivation? Is writing a good skill to have and thus merits practising?

In the margin and within the budget allocated to AI safety, the EA community has underspent on power concentration problems and overspent on AI control.

"It is appropriate for small donors to spend time finding small charities to support"

For:

  • Larger donors typically only have the ability to study large donation opportunities.

Against:

  • I think most small donors (such as myself) are pretty bad at gauging the evidence in areas they are not expert in.
2
Mo Putera
There's an interesting variant of this if you generalise "small charities" to "small giving opportunities", cf. Nadia Asparouhova's Helium Grants. This doesn't so much address your "against" point but sidesteps it by focusing on individuals not orgs, which from having spoken with some meta-funders is standard. 

Perhaps a better framing is: "On the margin, should we devote farmed animal welfare resources to improve the animals being farmed (e.g., via corporate campaigns) or devote resources to substituting farmed animals altogether via alternative proteins?"

What about Spanish? I would be interested because I could give it as a present.

5
libbypeet
You should check in with Tlön, whose aim is to "translates online content related to effective altruism (EA), existential risk, and global priorities research into multiple languages": https://tlon.team/

Have you considered translating it? It seems to me the typical lectors outside English speaking countries will not necessarily be fluent in that language.

9
Lucia
Was going to ask the same about Italian!  I’ve been trying to explain EA to my (often Catholic) Italian family and friends for a long time - I think they’d be very receptive to this book.
1
JDBauman
We may translate to German. Need to check with the publisher

I think GFI has claimed this in the past, and given their role of large coordinator of the area I’m inclined to believe their conterfactual importance. However the problem is that without a downstream model of how dollars convert into averted animal suffering, it is quite hard to prioritise between theories of change.

Hi Caroline, thanks for the reply. I think you are very right in that both approaches are complementary and we should support both. There’s even a chance that advocacy campaigns may end up creating momentum from which alternative proteins could benefit. It is also true that alternative proteins may be able to access funds that are not available to corporate advocacy campaigns or similar, not just VC but also government support. That may also be the reason why GFI is highlighting the environmental aspect which is an easier sell outside of EA or animal welfa... (read more)

3
Caroline Mills
I wholeheartedly agree :) Thanks, Pablo! 

I think there are good arguments why those actions might have indeed been horrible mistakes. But I’m also quite uncertain about what would have been the best course of action at the time. Eg, there’s a reasonable case that the best we might hope for is steering the development of AI. I unfortunately don’t know.

Let me give a non AI example: I find it reasonable that some EAs try to steer how factory farming works (most animal advocacy), despite I preferring no animal died or was tortured for food.

But on the other hand I believe people at leadership positions failed to detect and flag the FTX scandal ahead of time. And that’s a shame.

3
Holly Elmore ⏸️ 🔸
There’s no need for a group like yours to be implicated in AI company wheeling and dealing. Being connected to EA’s decisions has probably made the issue much more confusing for you than it should be— PauseAI is suited for local groups and only involves talking about the danger and giving grassroots support to AI Safety bills. That should obviously have been the sort of thing local EA groups did for AI Safety, but the AI Safety part of EA has always been this weird elitist conspiracy to have stake in the Singularity.

I don’t think we see much top-down leadership. There’s eg GiveWell, which I take seriously, but sometimes prioritising between different broad cause areas is very hard, and my understanding is that people in my local community feel the same way and are broadly supportive of diverse points of view.

2
Holly Elmore ⏸️ 🔸
So will you join me in denouncing the horrible mistakes around AI Safety like working with the labs that the actual people in control of the name EA have made?

I fought for EA to mean something simpler— just someone who 1. Figured out the best way to improve the world and 2. Does it— but I lost.

For what it is worth, this is not how I feel in my local EA community. There are people leading effective giving organisations and others who just go on with their usual lives with trial pledges; and I feel we are fairly non judgemental.

0
Holly Elmore ⏸️ 🔸
Why use the EA name? There is a leadership and they’re telling people where to donate that money and how to think. You have some responsibility for that.

I donated to (i) ARMoR (https://www.armoramr.org/), because I am convinced about the quality of their cost estimates and believe targeted policy interventions can be fairly tractable; (ii) and also to the Global Health Fund from Ayuda Efectiva (https://ayudaefectiva.org/fondo-salud-global), in part to encourage others to donate.

New anti-malaria treatment clears phase 3 trials.

I just found that there is a new anti-malarial alternative to artemisinin, the most common antimalarial chemical, which has successfully completed Phase 3 trials. Its nickname is GanLum and apparently has quite powerful effects:

A new drug, called GanLum, was more than 97% effective at treating malaria in clinical trials carried out across 12 African countries, researchers reported Wednesday at the American Society for Tropical Medicine and Hygiene in Toronto. That's as good, if not better, than the current

... (read more)
4
Yarrow Bouchard 🔸
Very interesting! And very hopeful! Thanks for sharing!

Hey Alex, thanks a lot for the post, and for the work you do at GFI.

Something I would love to read (and might write up this funding season) is how to compare the impact of GFI work with alternative proteins to other animal charities advocating working on corporate campaigns. This is highly non-obvious because GFI work depends on some theory of change, which I find very attractive, but for which I have not found good models. The closest is this post https://forum.effectivealtruism.org/posts/CA8a9JS3fYb63YWoh/the-humane-league-needs-your-money-more-than-alt-... (read more)

8
Alex Mayers @GFI 🌱
Hey Pablo, Thanks for your comment. We’re always happy to answer questions about our impact! It’s difficult to make a direct comparison between the impact of GFI’s work in alternative proteins and that of other animal advocacy organisations because the theory of change is so different. Advocacy campaigns can generate short-term wins for animals, but they don’t address the root causes of factory farming. GFI’s focus is on long-term, systemic change, transforming the entire food system by finding an alternative to conventional animal products that can feed the world with a fraction of the harm. This kind of change inevitably takes longer, but the potential scale of impact is much greater. GFI’s role is basically to make this transition faster and achieve this impact more quickly. You shared an article comparing the impact of donating to The Humane League with investing in alternative proteins, but flagged that you think it’s likely that supporting GFI is more effective than investing in individual companies, and therefore, this would be a better comparison of impact. We agree. Investing in alternative proteins by directly funding a pilot plant or factory can help one company scale faster, but it doesn’t solve the barriers holding back the sector, like missing infrastructure, unclear regulations, or limited public funding. Philanthropic support for GFI fills that gap. We help governments recognise alternative proteins as a strategic priority, direct investors toward opportunities, and support companies with the data, insights, and regulatory clarity they need to scale sustainably. Without this work, alternative proteins wouldn’t be seen as a credible or fundable opportunity by governments or investors, meaning every donated euro or dollar can have an outsized catalytic effect. It’s also worth saying that GFI has a broad base of supporters, with 80% of our donors giving between $1 and $1,000 each year. Collectively, those gifts have a much bigger impact than they c

I wonder how is ACE selecting charities? I wonder in particular because the Good Food Institute used to be considered a high-impact charity, but I have not seen any updates on that since 2022, when the assessment was broadly positive reference here. Not only that, but it seems GFI was probably one of the largest charities.

You can find more information about our selection process here. In 2024, GFI decided to postpone re-evaluation to a future year to allow their teams more time to focus on opportunities and challenges in the alternative proteins sector. They decided not to apply to be evaluated in 2025.

I am considering writing a brief post about how I think the EU AI office (where I will likely be starting a new position in one month) can address some issues of AI differently from other actors. The EU AI office might complement the work of traditional actors in addressing loss of control issues, but it could play a significant role in mitigating power concentration issues, especially in the geopolitical sense. This is a bit of a personal theory of change too.

I'd love someone to write how someone who feels most comfortable donating to the GiveWell top charities fund should address donating to animal charities. I know there exist ways like Animal Charity Evaluators Movement Grants, the Giving What We Can Effective Animal Advocacy fund, or the EA Animal Welfare Fund.

However, these all feel a bit different-flavoured than GiveWell's top charities fund in that they seem to be more opportunistic, small or actively managed; in contrast to GiveWell's larger, established, and typically more stable charities. This makes ... (read more)

Should small donors (~$10k per year) support small scale charities such as charity entrepreneurship incubated ones? Or would these charities be better supported by other larger founders?

6
Joey🔸
I don't think size is the best determiner. I think the seed network or mid-stage funding is probably higher EV at the cost of higher risk and more time to assess. I think if a donor finds getting into the weeds and speaking to the charities more fun I think they should go earlier stage. If they are time poor and want a reliable index fund I think it's hard to beat GW/ACE recs.

Since targeting Ultra High Net Worth Individuals seems to be a more effective strategy than broad donations (reference), to what extent do you think it is feasible to attract more such individuals to effective giving? What strategies are you particularly excited about researching and testing more extensively to do so?

8
Joey🔸
I am very optimistic about promising things being done in this area. I think being able to talk genuinely about multiple cause areas and being less directly pitchy on one worldview/NGO is a huge advantage a lot of EAs have. We are running a round on improving philanthropy and I would guess ideas we recommend there will be UHNW leaning. I wrote about a couple to do with dessert events and dragons den. Other things that are high on my list right now include grantmaker and philanthropic advisor training (a bit like our grantmaking training program), funder networks (like FAF but for other cause areas), more cross-cutting quizzes/tools (like GWWC's how rich are you tool). We are putting pretty active research into this over the next 6 months so I think I will have a better answer then, but on net, I think it's quite feasible there will be like 6 ideas we would be excited to see a full charity on - maybe 3 on HNWs.

To what extent the EA community should put more effort towards increasing the donation basis vs finding ever more impactful opportunities? What worries me the most in the second case is that while there might be some pretty good untapped opportunities to create new, more impactful charities, there is always too much uncertainty. For example, this is often argued as a reason to not prioritise funding Vitamin A supplementation (€3.5k/per live saved) vs malaria nets (€5.5k/per live saved), see this Ayuda Efectiva spreadsheet based on GiveWell data; which are already pretty heavily researched areas.

6
Joey🔸
I am probably more excited about outreach than research when it comes to high absorbancy opportunities like vitamin A vs malaria nets. I am probably most excited about research on things like family planning or livelihoods that we have not as a movement dug as deeply into and I think there are reasonable ethical views that would prioritize the top of those areas over the top of classic direct delivery global health.

What are, in your opinion, the most promising strategies to increase the amount of funding dedicated to effective charities?

2
Joey🔸
I like meta and I like HNW broadly as areas partly due to there already being a solid number of country-level effective giving organizations. More specific ideas within other comment.

To what extent would it make sense to consider the work by the Gates Foundation part of the effective giving ecosystem? I would argue that they are very effective, too, even if they have no association with effective altruism.

6
Luke Moore 🔸
Agree that they are focused on effectiveness and ss an ecosystem, we are increasingly building connections with the Gates Foundation. However, currently do not have enough information to be able to make a good conclusion regarding how much of their grantmaking is high-impact.  Hopefully at some point we can include info from the Gates Foundation's high-impact grants in this overview. 

I’m not sure about the cost effectiveness, but they have a quote by Michael Kremer in their webpage:

“The country where one is born is the most important determinant of extreme poverty. By facilitating international educational migration, Malengo offers very low-income youth the opportunity to dramatically increase both their own incomes, and those of their families. In my view, each dollar of donation to Malengo is likely to increase the incomes of program participants by more than would be the case for donations to virtually any other organization.“

Michael Kremer University Professor in Economics, University of Chicago Nobel Laureate in Economics, 2019

6
NickLaing
This could well be true. Although When it comes to "cost-effectiveness" of income gains through directly for the beneficiary (Kremers point) the early gains will have a much bigger effect on well-being. There's decent evidence that each doubling of income seems to have a similar effect on well-being. So "Cost per doubling of income" might be more useful metric than Kremer's cost per extra dollar generated. These studies also assume that they are living in the same economy, obviously things cost a lot more in Germany so we wouldn't expect well-being increases to be as big as if that income increase has happened in Uganda  https://forum.effectivealtruism.org/posts/coryFCkmcMKdJb7Pz/does-economic-growth-meaningfully-improve-well-being-a So if they were going to earn 500 euros a month in Uganda and they now earn 4000 in Germany, that might be better seen as a direct 3x increase in wellbeing pointes rather than 8x income. Even on the doubling-income front the program might still look very good (haven't looked into it). And I'm not touching on the other potential  benefits (remittances), just responding directly to Kremers comment.

Hi Emmannaemeka, Thanks for writing this, and sorry to hear that has been your experience so far. I don’t work in anything related to biology so I don’t think I can offer any solutions, unfortunately. The only thing that comes to mind, other than bio security, is that fermentation is one area that could be useful to produce alternative proteins. Perhaps the Good Food Institute could be a good place to look into. In any case, I think the EA community should be welcoming to everyone, even if there are no good ways to contribute to most typical EA causes. Again, thanks for writing this.

Thank you for your thoughtful response. I agree that pivoting can be useful, but I also believe that what we’re building at the Center for Phage Biology and Therapeutics has a unique and powerful kind of impact.


I often imagine the scenario of a patient who has run out of antibiotic options and is at the brink of death. In that moment, the clinician, or even the patient’s family, reaches out to us, sends us the bacterial isolate, and within days we are able to identify a matching phage, purify it, and return it for therapeutic use. That is not theoretical i... (read more)

As a successful entrepreneur and 10% pledger, do you have thoughts on whether the EA community should devote more efforts to earning to give? Should EAs be trying to start more for-profit startups?

3
Pablo Melchor 🔸
As I hinted at before, I am not a fan of the earning ro give concept and I much prefer an "earn and give" framing that recognizes that your income serves multiple purposes. Having said that, I do think that effective giving has a much larger role to play than it has today. Striving for The Most Impactful Career is great when it works but extremely frustrating when it doesn't. Adding giving to the equation expands your space of possibilities dramatically. As for starting for-profit startups, it is definitely an interesting option. I think the main considerations are the ones applicable to anyone contemplating entrepreneurship: the odds are against you and building something from scratch can be extremely hard, so you should only do it if you REALLY want to do it—often for hard to explain reasons.

Why did you decide to focus Ayuda Efectiva and the book almost only on global health only?

Thanks for the question, Pablo.

Beginning with Ayuda Efectiva, when we launched we had to decide how to approach what I would call a tough market: not much of a giving culture, low trust, and a still very traditional culture in certain aspects. I think that when you enter a market like that, your strategy must be wedge shaped. In our case, the tip of the wedge was making people consider whether they should give a part of their resources to help others. The wedge widened with the introduction of an effectiveness mindset and spatial impartiality (as referred ... (read more)

How successful do you think Ayuda Efectiva is with respect to your expectations before funding it? Any recommendations for founders of other effective giving organisations on what are the most important factors contributing to its success?

My standard reply when people ask me how Ayuda Efectiva is going is "happy but not satisfied". I am happy because the trend is good. This is money raised for effective charities:

I am not satisfied because our figures are still tiny and I would like to see at least an extra zero to the right.

I expected this to be a very hard endeavor and I told my board from day one that we were starting a long-distance race. I would therefore say that things are going more or less as I could have wished for. (Note: I think figures are a great a progress indicator but a bad... (read more)

PabloAMC 🔸
3
0
0
90% agree

I'd be doing less good with my life if I hadn't heard of effective altruism

I think the EA community has significantly encouraged me to do significantly more good, if only because I became vegetarian and signed the 10% pledge.

As the post says, it may be worth for europeans to provide feedback to the EU Commission on the new animal welfare public consultation: https://ec.europa.eu/info/law/better-regulation/have-your-say/initiatives/14671-On-farm-animal-welfare-for-certain-animals-modernisation-of-EU-legislation_en

I think we agree. Thinking out loud: Perhaps the community should consider a way to have a more transparent way of making these decisions. If we collectively decide to follow large funders, but are unable to understand their motives, it is impossible to have fund diversification.

I think this makes sense, but it seems kind of disconnected from the presentation, which seemed to indicate CAIP proposes reasonable policy and has a strong team. Perhaps Jason can clarify why he thinks major donors have passed on this opportunity.

I wish I could! Unfortunately, despite having several conversations and emails with the various AI safety donors, I'm still confused about why they are declining to fund CAIP. The message I've been getting is that other funding opportunities seem more valuable to them, but I don't know exactly what criteria or measurement system they're using.

At least one major donor said that they were trying to measure counterfactual impact -- something like, try to figure out how much good the laws you're championing would accomplish if they passed, and then ask how clo... (read more)

8
Neel Nanda
I do not feel qualified to judge the effectiveness of an advocacy org from the outside - there's a lot of critical information like whether they're offending people, if they're having an impact, whether they're sucking up oxygen from other orgs in the space, if their policy proposals are realistic, if they're making good strategic decisions, etc, that I don't really have the information to evaluate. So it's hard to engage deeply with an org's case for itself, and I default to this kind of high level prior. Like, the funders can also see this strong case and still aren't funding it, so I think my argument stands

That is actually a good point, thanks Jason.

The key objection I always have to starting new charities, as Charity Entrepreneurship used to focus on is that I feel is money usually not the bottleneck? I mean, we already have a ton of amazing ideas of how to use more funds, and if we found new ones, it may be very hard to reduce the uncertainty sufficiently to be able to make productive decisions. What do you think Ambitious Impact ?

A new organization can often compete for dollars that weren't previously available to an EA org -- such as government or non-EA foundation grants that are only open to certain subject areas. 

I agree there is certainly quite a lot of hype, though when people want to hype quantum they usually target AI or something. My comment was echoing that quantum computing for material science (and also chemistry) might be the one application where there is good quality science being made. There are also significantly less useful papers, for example those related to "NISQ" (non-error-corrected) devices, but I would argue the QC community is doing a good job at focusing on the important problems, not just hyping around.

Hi there, I am a quantum algorithm researcher at one of the large startups in the field and I have a couple of comments, one to back up the conclusion on ML for DFT, and another to push back a bit on the quantum computing end.

For the ML for DFT, one and a half years ago we tried (code here) to replicate and extend the DM21 work, and despite some hard work we failed to get good accuracy training ML functionals. Now, this could be because I was dumb or lacked abundant data or computation, but we mostly concluded that it was unclear how to make ML-based funct... (read more)

4
titotal
Hey, thanks for weighing in, those seem like interesting papers and I'll give them a read through.  To be clear, I have very little experience in quantum computing, and haven't looked into it that much and so I don't feel qualified to comment on it myself (hence why this was just an aside there). All I am doing is relaying the views of prominent professors in my field, who feel very strongly that it is overhyped and were willing to say so in the panel, although I do not recall them giving much detail on why they felt that way. This matches with the general views I've had with other physicists in casual conversations. If I had to guess the source of these views, I'd say it was skepticism of the ability to actually build such large scale fault-tolerant systems. Obviously this is not strong evidence and should not be taken as such. 

I think this had to do more with GDPR than the AI act, so the late release in the EU might be a one-off case. Once you figure out how to comply with data collection, it should be straightforward to extend to new models, if they want to.

5
Manuel Allgaier
I did not say that this was due to the EU AI Act, agree that GDPR seems more likely. I mentioned it as an example of EU regulation leading to an AI Lab delaying their EU launch / deprioritizing the EU. 

My point is that slowing AI down is often an unwanted side effect, from the regulator perspective. Thus, the main goal is raising the bar for safety practices across developers.

I don’t think the goal of regulation or evaluations is to slow down AGI development. Rather, the goal of regulation is to standardise minimal safety measures (some AI control, some security etc across labs) and create some incentives for safer AI. With evaluations, you can certainly use them for pausing lobbying, but I think the main goal is to feed in to regulation or control measures.

1
Esben Kran
The main effect of regulation is to control certain net negative outcomes and hence slowing down negative AGIs. RSPs that require stopping developing at ASL-4 or otherwise are also under the pausing agenda. It might be a question of semantics due to how Pause AI and the Pause AI Letter have become the memetic sink for the term pause AI?

My donation strategy:

It seems that we have some great donation opportunities in at least some cases such as AI Safety. This has made me wonder what donation strategies I prefer. Here are some thoughts, also influenced by Zvi Mowshowitz's:

  1. Attracting non-EA funding to EA causes: I prefer donating to opportunities that may bring external or non-EA funding to some causes that EA may deem relevant.
  2. Expanding EA funding and widening career paths: Similarly, if possible fund opportunities that could increase the funds or skills available to the community in the
... (read more)

I agree with most except perhaps the framing of the following paragraph.

Sometimes that seems OK. Like, it seems reasonable to refrain from rescuing the large man in my status-quo-reversal of the Trolley Bridge case. (And to urge others to likewise refrain, for the sake of the five who would die if anyone acted to save the one.) So that makes me wonder if our disapproval of the present case reflects a kind of speciesism -- either our own, or the anticipated speciesism of a wider audience for whom this sort of reasoning would provide a PR problem?

In my o... (read more)

For what is worth, I like the work of Good Food Institute on pushing the science and market of alternative proteins. They also do some policy work though I fear their lobbying might have orders of magnitude less strength than the industry’s.

Also, as far as I know the Shrimp Welfare Initiative is directly buying and giving away the stunners (hopefully to create some standard practice around it). So counterfactually it seems a reasonable bet for the direct impact at least.

But I resonate with the broad concerns with corporate outreach and advocacy. I am parti... (read more)

Hey Vasco, on a constructive intention, let me explain how I believe I can be a utilitarian, maybe hedonistic to some degree, value animals highly and still not justify letting innocent children die, which I take as a sign of the limitations of consequentialism. Basically, you can stop consequence flows (or discount them very significantly) whenever they go through other people's choices. People are free to make their own decisions. I am not sure if there is a name for this moral theory, but it would be roughly what I subscribe to.

I do not think this is an ideal solution to the moral problem, but I think it is much better than advocating to let innocent children die because of what they may end up doing.

9
Vasco Grilo🔸
Thanks, Pablo. I appreciate the effort to be construcive. However, I have a hard time parsing what you are suggesting. All moral actions depend on humans' decisions to some extent, so it looks like everything would be in equal footing. One could argue we should discount more consequences which depend more on humans' decisions, but I do not understand what this means. In my mind, one should simply weight consequences according to their probabilities.

I donated the majority of my yearly donations to a campaign for AMF I did through Ayuda Efectiva for my wedding. The goal was to promote effective donations in my family and friends. I also donated a small amount to the EA Forum election because I think it is good for democratic reasons to allow the community to decide where to allocate some funds.

1
Pat Myron 🔸
Would love to hear more about how the wedding campaign went!

Hi @Jbentham,

Thanks for the answer. See https://forum.effectivealtruism.org/posts/K8GJWQDZ9xYBbypD4/pabloamc-s-quick-takes?commentId=XCtGWDyNANvHDMbPj for some of the points. Specifically, the problem I have with the post is not about cause prioritization or cost-effectiveness.

Arguing that people should not donate to global health doesn't even contradict common-sense morality because as we see from the world around us, common-sense morality holds that it's perfectly permissible to let hundreds or thousands of children die of preventable diseases.

I thin... (read more)

Hi there,

Let me try to explain myself a bit.

For example, global health advocates could similarly argue that EA pits direct cash transfers against interventions like anti-malaria bednets, which is divisive and counterproductive, and that EA forum posts doing this will create a negative impression of EA on reporters and potential 10% pledgers.

There is a difference between what the post does and what you mention. The post is not saying that you should prioritize animal welfare vs global health (which I would find quite reasonable and totally acceptable). ... (read more)

9
Erich_Grunewald 🔸
Hmm, but we are all letting children die all the time from not donating. I am donating just 15% of my income; I could certainly donate 20-30% and save additional lives that way. I think my failing to donate 20-30% is morally imperfect, but I wouldn't call it repugnant. What is it that makes "I won't donate to save lives because I think it creates a lot of animal suffering" repugnant but "I won't donate to save lives because I prefer to have more income for myself" not?

As I commented above, it would not make any sense for someone caring about animals to kill people.

You only did so on the ground of not being an effective method, and because it would decrease support for animal welfare. Presumably, if you could press a button to kill many people without anyone attributing it to the animal welfare movement you would, then?

2
Vasco Grilo🔸
No. I guess that would increase welfare neaterm, but could increase or decrease it overall due to uncertain longer term effects. More importantly, killing people would make me feel bad even if I was the only who would ever know about it. This would decrease my productivity and donations to the best animal welfare interventions, which would be the dominant consideration given my estimate that one can neutralise the negative effects on animals of one person in 2022 with just a few cents. I strongly endorse impartiality. So, if forced to pick between X and Y, and it is stipulated that X increases impartial welfare more than Y despite involving killing people, I would pick X. However, I do not see anything in the real world coming anywhere close to that.
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