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Lab-grown meat approved for pet food in the UK  "The UK has become the first European country to approve putting lab-grown meat in pet food. Regulators cleared the use of chicken cultivated from animal cells, which lab meat company Meatly is planning to sell to manufacturers. The company says the first samples of its product will go on sale as early as this year, but it would only scale its production to reach industrial volumes in the next three years."
I think it is good to have some ratio of upvoted/agreed : downvotes/disagreed posts in your portfolio. I think if all of your posts are upvoted/high agreeance then you're either playing it too safe or you've eaten the culture without chewing first.
A couple takes from Twitter on the value of merch and signaling that I think are worth sharing here: 1)  2) 
Do you like SB 1047, the California AI bill? Do you live outside the state of California? If you answered "yes" to both these questions, you can e-mail your state legislators and urge them to adopt a similar bill for your state. I've done this and am currently awaiting a response; it really wasn't that difficult. All it takes is a few links to good news articles or opinions about the bill and a paragraph or two summarizing what it does and why you care about it. You don't have to be an expert on every provision of the bill, nor do you have to have a group of people backing you. It's not nothing, but at least for me it was a lot easier than it sounded like it would be. I'll keep y'all updated on if I get a response.
What is "capabilities"? What is "safety"? People often talk about the alignment tax: the magnitude of capabilities/time/cost a developer loses by implementing an aligned/safe system. But why should we consider an unaligned/unsafe system "capable" at all? If someone developed a commercial airplane that went faster than anything else on the market, but it exploded on 1% of flights, no one would call that a capable airplane. This idea overlaps with safety culture and safety engineering and is not new. But alongside recent criticism of the terms "safety" and "alignment", I'm starting to think that the term "capabilities" is unhelpful, capturing different things for different people.

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mako yass commented on Silent cosmic rulers

In this post, I wish to outline an alternative picture to the grabby aliens model proposed by Hanson et al. (2021). The grabby aliens model assumes that “grabby aliens” expand far and wide in the universe, make clearly visible changes to their colonized volumes, and immediately...

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Refuting 3: Life/history simulations under visible/grabby civs would far outnumber natural origin civs under quiet regimes.

May 2024 marked the last month of the Center for Effective Aid Policy. This post serves as the public post-mortem. I have strived for it to be interesting to the average forum reader, who may not know much about the cause area.

For professionals in development, we have a...

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A on the other hand only has a backroom of STEM people and no frontroom at all, leaving massive value on a non-table that never gets communicated to the world it was for.

I don't understand this sentance. The value on the table is good ideas that don't get realised because they're poorly communicated?

This is a reminder announcement that applications for Pathways to Progress’ book discussion series close on Sunday, July 21st at 11:59 PM ET.

We aim to create a community of individuals committed to exploring and contributing to human prosperity. We will discuss technological and scientific innovation to foster a deep understanding of the mechanisms behind human advancement. Readings will investigate historical examples of progress, the implications of economic growth on moral progress, and the relationship between technological progress and societal change.

We will meet bi-weekly over Zoom to discuss a book, followed by a Q&A conversation with the author. We will have regular podcast-style conversations with other guests, who currently include Alec Stapp, Rasheed Griffiths, and Kurtis Lockhart. We will post conversations on our YouTube channel.

Here are the details on our...

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You'll get a weekly email with the best posts from the past week. The Forum team selects the posts to feature based on personal preference and Forum popularity, and also adds some announcements and a classic post.

The meat-eater problem is often overlooked in discussions of effective neartermist charities. If one takes the concern seriously and cares about animal welfare, saving human lives or increasing income in developing countries (e.g. bed nets) could be net-negative and create...

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Wow, that's not something I had completely considered. Do you have any thoughts on how to address this flow-through effect/estimate it's impact?

I just wrote an article on my Substack against Utilitarianism. Just thought I would share it here. 

Some main points I go over are: critiques of impartiality, population ethics, the utility monster, incommensurability, accounting for other values, and cluelessness. ...

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I only skimmed it but this looks like a great article, thanks for sharing!

This post is a write-up of my talk from EA Global: Bay Area 2024, which has been lightly edited for clarity. 

Speaker background

Jeffrey is the Executive Director of Palisade Research, a nonprofit that studies AI capabilities to better understand misuse risks from current...

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Title should be "AI companies . . ."

Thanks! I've updated the title.

Epistemic status: This is a summary of an 80-page law review article that took me ~6 months to research and write. I am highly confident about my characterization of existing U.S. tort law and its limits. This characterization is only contested by other legal scholars and...

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Eliminating the malice or recklessness requirement and allowing punitive damages calculations to account for unrealized uninsurable risk are both big asks to make of common law courts.

Would it make a difference if the risks were insured? 

Tyner commented on The Precipice Revisited

I'm often asked about how the existential risk landscape has changed in the years since I wrote The Precipice. Earlier this year, I gave a talk on exactly that, and I want to share it here.

Here's a video of the talk and a full transcript.


In the years since I wrote...

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Toby - I appreciated reading your updates based on the events of the last 5ish years.

I'm am wondering if you have also reconsidered the underlying analyses and assumptions that went into your initially published models?  There's been a fair amount written about this; to me the best is from David Thorstad here:

I would really value you engaging with the arguments he or others present, as a second kind of update.


This detailed analysis by Karam Elabd and Ryan Duncombe, PhD, evaluates the cost-effectiveness of the new R21 malaria vaccine in comparison to other existing interventions such as insecticide-treated bed nets (ITNs), seasonal malaria chemoprevention (SMC), and mosquito control. They crunched the data into 2024 US dollars and found that the R21 vaccine is just about as cost-effective as those trusty bed nets.

1. Cost-Effectiveness Comparison:

  • The R21 vaccine has a cost per disability-adjusted life year (DALY) averted of $39.
  • Insecticide-treated bed nets (ITNs) have a cost per DALY averted of $38.

2. Delivering a Year of Healthy Life for Less Than $50:

  • Both the R21 vaccine and ITNs deliver a year of healthy life for less than $50, as their cost per DALY averted (less than $40) falls well within this range.
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