Impressions from the 21st Annual U.S. Cluster Headache Patient Conference, organized by Clusterbusters. On the morning of the last day of the conference, E. was hanging out with other “clusterheads” outside the conference hotel when he started having a cluster headache attack. Before he could go back to his hotel room, J. offered E. his DMT v...

TL;DR:  The movement has an evidence problem. To solve it, for each intervention we need to know: * What types of evidence that intervention needs * What types of evidence different sources can give us In this post, we outline a framework for evidencing an intervention through five stages: ...

Cross-posted from my Substack. Epistemic status: I’ve puzzled over this for a long time but I’m not sure I came to the right answers. I'm sharing this partly because it might help others work on resource allocation, but mostly because some smarter reader might tell me how to do it better. TL;DR: * I he...