This is a post written by David Thorstad, a philosophy professor who maintains a blog for criticizing various tenets of effective altruism called Reflective Altruism, as part of a series of on human biodiversity (HBD), a modern iteration of so-called race science. HBD, of course, isn't typical fare for EA, or any of its championed causes. Yet it has, to much controversy over the years, been recognized as a subject of interest among prominent thinkers associated with either the effective altruism or rationality communities, or others writers they've been affiliated with. This latest post in Thorstad's series provides a critical overview of @Scott Alexander's history of engagement with said body of ideas, both on his current blog, Astral Codex Ten (ACX), as well as before then, such as on his previous blog, Slate Star Codex (SSC).
I think it, like much of Scott's work, is written with a "micro-humorous" tone but reflect to a significant extent his genuine views – in the case you quoted, I see no reason to it's not his genuine view that building Trump's wall would be a meaningless symbol that would change nothing, with all that implies of scorn toward both #BuildTheWall Republicans and #Resistance Democrats.
Another example, consider these policy proposals:
Months later he replied this to an anonymous ask on the subject:
Do Scott actually believe the Achaemenid Empire should be restored with Zoroastrianism as state religion? No, "that was *kind of* joking, and [he doesn't] know anything about foreign policy, and this is probably the worst idea ever". Does this still reflect a coherent set of (politically controversial) beliefs about foreign policy which he clearly actually believe (e.g. that "Bashar al-Assad [...] kept the country at peace" and Syrian oppositionists were all "Al-Qaeda in disguise"), that are also consistent with him picking Tulsi Gabbard as Secretary of State in his "absurdist humor"? Yeah, it kinda does. Same applies, I think, to the remainder of his post.