Announcing Our Largest Grant to Date

This is a new episode of the GiveWell Conversations podcast. You can listen to the episode or read a summary of the conversation below.

GiveWell, with co-funding from Coefficient Giving, recently made our largest grant to date: $276 million to the Against Malaria Foundation (AMF) to support the procurement and distribution of 92 million nets in the Democratic Republic of the Congo (DRC) from 2027 through 2029. We estimate that the nets, 46 million of which we think would not otherwise be distributed, will avert roughly 67,000 deaths. We have supported AMF’s work for more than 15 years, and the insecticide-treated nets it procures and distributes remain one of the most cost-effective ways we’ve found to save lives.

This grant, which involved a more rigorous investigation process than most, is part of a larger story about scaling our team and systems to handle substantially more funding while deepening our research rigor. Last year, we directed more than $400 million to highly cost-effective programs to save and improve lives and, this year, we expect our grantmaking to approach, and possibly exceed, $1 billion. This increase in grantmaking aims to meet global needs faster and more effectively.

In this episode, GiveWell co-founder and CEO Elie Hassenfeld speaks with Senior Program Officer Alex Bowles about the questions the team set out to answer during the grant investigation.

Elie and Alex discuss:

• Assessing the impact of insecticide-treated nets in DRC: GiveWell usually estimates a program’s cost-effectiveness and impact by analyzing academic evidence, particularly randomized trials, and making a number of adjustments. Because of our growing capacity, we were able to do something new for this grant: We tested our assumptions about DRC’s past net campaigns by drawing on two new, independent lines of evidence. First, we analyzed a recent national survey, which showed a reduction in malaria infections close to what we had predicted. Second, we commissioned a firm based in DRC to interview households and community leaders. Those interviews confirmed records about nets received and provided information about the challenges of conducting net campaigns in DRC. Taken together, this more robust approach increased our confidence that nets work well and are likely to reach intended households in the locations funded by this grant.
• Planning and coordinating at scale: This grant is nearly three times the size of our previous largest grant (also to AMF) and is concentrated in one country rather than being spread across several. The grant commits funds at the beginning of a multi-year planning cycle, which we think will make these campaigns easier to plan. It also aims to ensure that campaigns happen across all 26 of DRC’s provinces, in some cases on an expedited timeline. This shift in our funding approach makes close coordination with AMF and other partners—including the Global Fund, which is funding much of the net distribution, and the national malaria program—even more important than before.
• Rethinking how often nets are distributed: In most countries, nets are distributed every three years, but evidence shows that nets wear out more quickly in DRC, in part because of the climate. Our analysis of national survey data, net durability studies, and AMF’s post-distribution monitoring suggests that nets in DRC last roughly 18 to 24 months. DRC had already shortened its campaign cycle, aiming to distribute nets every 30 months. With the support of the government, GiveWell is supporting net campaigns every 24 months in several provinces with high rates of malaria transmission, and funding evidence gathering so we can learn whether more frequent net campaigns is a cost-effective strategy for further reducing malaria rates. We think this approach will help further prevent malaria and potentially save more lives.

A larger, more experienced team enabled us to investigate this grant more deeply than we could have even two years ago—looking back at past grants to assess their estimated impact and asking important questions about the challenges of implementing such a large program. The same capacity that allowed us to research this grant, which we expect to save tens of thousands of lives, is also helping us look ahead to newer strategies that could save even more lives in the future.

Visit our All Grants Fund and Top Charities Fund pages to learn more about how you can support this work, and listen or subscribe to our podcast for our latest updates.

This episode was recorded on August 14, 2026, and represents our best understanding at that time.