Casting a Wider Net for Cost-Effective Programs

This is a new episode of the GiveWell Conversations podcast. You can listen to the episode or read a summary of the conversation below.

GiveWell tends to be known for its work in areas like malaria prevention, water treatment, and nutrition. But as our research team has grown, so has our ability to search for cost-effective programs across a much wider range of issues.

Serious health problems, such as lack of medical oxygen and stockouts of essential medicines at health facilities, affect millions of people in low-income countries. There may be highly cost-effective solutions to these problems that haven’t been thoroughly evaluated or adequately funded. One of the ways GiveWell is searching for these solutions is through the new areas research subteam, which investigates programs in cause areas GiveWell hasn’t historically focused on.

In this episode, GiveWell co-founder and CEO Elie Hassenfeld speaks with Senior Program Officer Dan Brown about GiveWell’s new areas research subteam and three grants that illustrate the team’s work.

Elie and Dan discuss:

• Evaluating whether electronic tracking can improve access to health supplies: In many low- and middle-income countries, health facilities track their medicine supplies on paper, with stock counted roughly once a month for only a subset of products. As a result, staff may be less able to accurately predict inventory levels. This can lead to stockouts, making it more difficult for people to access the treatment they need, or to surplus commodities, which could result in expired medicines. GiveWell is funding the Clinton Health Access Initiative (CHAI), mSupply Foundation, and University of California, Berkeley to implement an electronic supply chain management system in health facilities in Laos and conduct a randomized controlled trial measuring whether the system reduces stockouts and improves patients’ access to the treatments they need. If we learn that more people are able to access treatment as a result, funding the rollout of this type of software in countries facing higher burdens of disease could be a cost-effective strategy for reducing mortality. 
• Supporting a new approach to medical oxygen production: Medical oxygen is essential for treating severe pneumonia, malaria, and many other health conditions—yet access in low-income countries remains limited. GiveWell is funding PATH to assess the market viability of a recently developed oxygen-producing device that appears to require far less maintenance than existing technology. This is an early-stage investment focused on understanding manufacturing costs and potential demand. PATH’s work will run concurrently with research funded by other organizations assessing whether the device works effectively in real-world conditions in low-income countries. We’re also investigating other opportunities to improve the ability to diagnose low oxygen and increase access to a reliable oxygen supply in health facilities. 
• Investigating a caregiver training program for newborn health: Noora Health’s Care Companion Program trains family members in practices that support maternal and newborn health, including skin-to-skin contact, breastfeeding techniques, and how to recognize illness warning signs. The existing evidence base for these practices is limited to one study without a control group (making it difficult to assess if the practices actually caused the results), so GiveWell is funding two studies in India: a pilot study assessing intermediate health outcomes like sepsis and umbilical cord infections that are linked to newborn mortality, and a larger randomized controlled trial measuring the program’s effect on neonatal mortality. We expect that these studies will provide additional evidence needed to assess whether to fund the program at scale, potentially reducing childhood deaths.

These grants reflect just a few of the ways GiveWell’s research is expanding to identify more high-impact opportunities to help people. GiveWell is hiring to expand our research team further—including positions on the new areas subteam—so we can cover more ground and ultimately direct more donor funding faster to programs where it can do extraordinary good.

Visit our All Grants Fund page to learn more about how you can support this work, and listen or subscribe to our podcast for our latest updates.

This episode was recorded on June 12, 2026, and represents our best understanding at that time.