This is a linkpost for https://confusopoly.com/2019/04/03/the-optimizers-curse-wrong-way-reductions/.
Summary
I spent about two and a half years as a research analyst at GiveWell. For most of my time there, I was the point person on GiveWell’s main cost-effectiveness analyses. I’ve come to believe there are serious, underappreciated issues with the methods the effective altruism (EA) community at large uses to prioritize causes and programs. While effective altruists approach prioritization in a number of different ways, most approaches involve (a) roughly estimating the possible impacts funding opportunities could have and (b) assessing the probability that possible impacts will be realized if an opportunity is funded.
I discuss the phenomenon of the optimizer’s curse: when assessments of activities’ impacts are uncertain, engaging in the activities that look most promising will tend to have a smaller impact than anticipated. I argue that the optimizer’s curse should be extremely concerning when prioritizing among funding opportunities that involve substantial, poorly understood uncertainty. I further argue that proposed Bayesian approaches to avoiding the optimizer’s curse are often unrealistic. I maintain that it is a mistake to try and understand all uncertainty in terms of precise probability estimates.
I go into a lot more detail in the full post.
FWIW, as someone who was and is broadly sympathetic to the aims of the OP, my general impression agrees with "excessive quantification in some areas of the EA but not enough of it in other areas."
(I think the full picture has more nuance than I can easily convey, e.g. rather than 'more vs. less quantification' it often seems more important to me how quantitative estimates are being used - what role they play in the overall decision-making or discussion process.)