Update, 12/7/21: As an experiment, we're trying out a longer-running Open Thread that isn't refreshed each month. We've set this thread to display new comments first by default, rather than high-karma comments.
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If humanity survives, we have a decent shot of reducing suffering in nature and spreading utopia throughout the stars.
If humanity dies, but not all life, and some other species eventually evolves intelligence and then builds civilization, I think they might also have a shot of doing the same thing, but this is more speculative and uncertain, and seems to me to be a much worse bet than betting on humanity (flawed as we are).